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Aquazide H and Wytensin

Determining the interaction of Aquazide H and Wytensin and the possibility of their joint administration.

Check result:

Aquazide H <> Wytensin

Relevance: 02.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The bioavailability of hydrochlorothiazide is greater when it is given with guanabenz than when it is given alone. The mechanism is not known, but it is suspected that guanabenz increases the gastrointestinal transit time of hydrochlorothiazide. No clinical intervention appears to be necessary.

References

Chiang ST, White GR, Spangler T, et al "Effects of guanabenz on gastrointestinal absorption of hydrochlorothiazide." J Cardiovasc Pharmacol 6 (1984): s771-5

Aquazide H

Generic Name: hydrochlorothiazide

Brand name: Aquazide H, HydroDIURIL, Microzide,

Synonyms: Aquazide H (Oral)

What is Aquazide H?

Wytensin

Generic Name: guanabenz

Brand name:

Synonyms: Wytensin (Oral)

What is Wytensin?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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