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Arava and Insta-Char

Determining the interaction of Arava and Insta-Char and the possibility of their joint administration.

Check result:

Arava <> Insta-Char

Relevance: 25.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using charcoal together with leflunomide. Using these medications together can make leflunomide less effective. Do not take charcoal with any other medication. Charcoal binds to other drugs and reduces their effectiveness, which could become dangerous. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: A significant decrease in M1, the active metabolite of leflunomide, has resulted when cholestyramine or activated charcoal is administered to patients receiving leflunomide. Administration of cholestyramine 8 grams 3 times a day has resulted in a 40% decrease in plasma levels of M1 in a 24 hour period.

MANAGEMENT: Coadministration of these drugs is not recommended.

References

"Product Information. Arava (leflunomide)." Hoechst Marion-Roussel Inc, Kansas City, MO.

Arava

Generic Name: leflunomide

Brand name: Arava

Synonyms: n.a.

What is Arava?

Insta-Char

Generic Name: charcoal

Brand name: Actidose-Aqua, Activated Charcoal, Charcoal Plus DS, EZChar, Insta-Char, Liqui-Char, Optimum Charcoal, Liqui-Char with Sorbitol, Charcocaps, Activated Charcoal with Sorbitol, Charcoaid 2000, Charcoaid-G, Char-Flo with Sorbitol, Charcoaid, Charcodote, Char-Flo Aqueous Base, Actidose-Aqua Advance, JL. Bragg's Medicinal Charcoal, Medicoal, Karbons, Carbomix, Carbosorb X, Charcotabs, Healthstream Activated Charcoal, Charcotrace, Chem Mart Nasal Decongestant Capsule, Pharmacia Carbosorb, Norit, Eucarbon, Active Carbon

Synonyms: n.a.

What is Insta-Char?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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