Arestin eent and Zegerid (Omeprazole and Sodium Bicarbonate Capsules)
Determining the interaction of Arestin eent and Zegerid (Omeprazole and Sodium Bicarbonate Capsules) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using sodium bicarbonate together with minocycline may decrease the effects of minocycline. Administration of sodium bicarbonate and minocycline should be separated by three to four hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Alkalinization of the urine may decrease the plasma concentration of some tetracyclines. The mechanism is not completely understood, but may involve increased renal elimination of tetracyclines when the urine becomes alkalinized. Information is available for doxycycline, tetracycline, and sodium bicarbonate only.
MANAGEMENT: If these drugs must be used together, an alternating dosing schedule is recommended (three to four hours apart).
- Elliott GR "Sodium bicarbonate and oral tetracycline." Clin Pharmacol Ther 13 (1972): 459
- Jaffe JM, Colaizzi JI, Poust RI, McDonald RH Jr "Effect of altered urinary pH on tetracycline and doxycycline excretion in humans." J Pharmacokinet Biopharm 1 (1973): 267-82
- Jaffe JM, Poust RI, Feld SL, Colaizzi JL "Influence of repetitive dosing and altered urinary pH on doxycycline excretion in humans." J Pharm Sci 63 (1974): 1256-60
Generic Name: minocycline
Brand name: Dynacin, Minocin, Minocin PAC, Minolira, Solodyn, Ximino, Vectrin, Myrac
Synonyms: Minocycline, Minocycline (Systemic)
Generic Name: omeprazole / sodium bicarbonate
Brand name: Zegerid, Zegerid OTC
Synonyms: Zegerid
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Arestin eent-Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)
- Arestin eent-Zegerid OTC
- Arestin eent-Zejula
- Arestin eent-Zelapar
- Arestin eent-Zelapar Oral
- Arestin eent-Zelboraf
- Zegerid (Omeprazole and Sodium Bicarbonate Capsules)-Arestin mucous membrane powder
- Zegerid (Omeprazole and Sodium Bicarbonate Capsules)-Arformoterol
- Zegerid (Omeprazole and Sodium Bicarbonate Capsules)-Arformoterol inhalation
- Zegerid (Omeprazole and Sodium Bicarbonate Capsules)-Arformoterol Tartrate
- Zegerid (Omeprazole and Sodium Bicarbonate Capsules)-Argatroban
- Zegerid (Omeprazole and Sodium Bicarbonate Capsules)-Argatroban Intravenous