Argatroban and Heparin and Dextrose

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using heparin together with argatroban is not recommended. Combining these medications can increase the risk of bleeding. Moreover, you should not use any product containing heparin if you are being treated for, or have a history of, heparin-induced thrombocytopenia. Consult with your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

CONTRAINDICATED: The concomitant use of heparin and direct thrombin inhibitors may increase the risk of bleeding complications due to additive or synergistic effects on the clotting cascade. Moreover, since direct thrombin inhibitors are used for the treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT) and for anticoagulation in patients with or at risk for HIT, heparin would not be indicated in these patients.

MANAGEMENT: Patients with known HIT should not receive any heparin. All formulations of heparin, including heparin lock flush, should be withdrawn prior to and during the treatment of heparin-induced thrombocytopenia. Clinicians should allow sufficient time for heparin's effect on the activated partial thromboplastin time (aPTT) to decrease prior to initiation of the thrombin inhibitor. Close clinical and laboratory observation for bleeding complications is recommended.

Argatroban

Generic Name: argatroban

Brand name: Acova

Synonyms: n.a.

What is Argatroban?

Heparin and Dextrose

Generic Name: heparin

Brand name: Hep-Pak, Heparin Lock flush, Hep-Pak CVC, Hep-Lock, Heparin Sodium ADD-Vantage, HepFlush

Synonyms: Heparin Injection, Heparin

What is Heparin and Dextrose?