Argatroban Intravenous and Fedratinib Hydrochloride
Determining the interaction of Argatroban Intravenous and Fedratinib Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: Concomitant use of thrombin inhibitors and antiplatelet agents may increase the risk of bleeding complications due to additive or synergistic effects on the clotting cascade. MANAGEMENT: Coadministration of thrombin inhibitors and antiplatelet agents should be undertaken with caution and only after thorough assessment of risks and benefits. Close clinical and laboratory observation for bleeding complications is recommended. References "Product Information. Angiomax (bivalirudin)" The Medicines Compny, Cambridge, MA. "Product Information. Acova (argatroban)" SmithKline Beecham, Philadelphia, PA. "Product Information. Refludan (lepirudin)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Professional:MONITOR: Concomitant use of thrombin inhibitors and antiplatelet agents may increase the risk of bleeding complications due to additive or synergistic effects on the clotting cascade.
MANAGEMENT: Coadministration of thrombin inhibitors and antiplatelet agents should be undertaken with caution and only after thorough assessment of risks and benefits. Close clinical and laboratory observation for bleeding complications is recommended.
- "Product Information. Angiomax (bivalirudin)" The Medicines Compny, Cambridge, MA.
- "Product Information. Acova (argatroban)" SmithKline Beecham, Philadelphia, PA.
- "Product Information. Refludan (lepirudin)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Generic Name: argatroban
Brand name: Acova
Synonyms: Argatroban (Intravenous)
Generic Name: fedratinib
Brand name: Inrebic
Synonyms: Fedratinib
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Argatroban Intravenous-Feiba
- Argatroban Intravenous-Feiba NF
- Argatroban Intravenous-Feiba VH Immuno
- Argatroban Intravenous-Feiba-VH
- Argatroban Intravenous-Felbamate
- Argatroban Intravenous-Felbamate Oral Suspension
- Fedratinib Hydrochloride-Arginine
- Fedratinib Hydrochloride-Arginine Intravenous
- Fedratinib Hydrochloride-Aricept
- Fedratinib Hydrochloride-Aricept (Donepezil 23 mg Tablets)
- Fedratinib Hydrochloride-Aricept (Donepezil Tablets)
- Fedratinib Hydrochloride-Aricept ODT