Aricept (Donepezil 23 mg Tablets) and Neostigmine Methylsulfate
Determining the interaction of Aricept (Donepezil 23 mg Tablets) and Neostigmine Methylsulfate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using neostigmine together with donepezil can increase the blood levels or add to the side effects of either medication. This can cause nausea, vomiting, diarrhea, abdominal pain, increased salivation, cold sweats, slow or irregular heartbeat, muscle weakness or cramps, dizziness, headache, seizures, or breathing problems. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: A synergistic effect may be expected when acetylcholinesterase inhibitors are administered concurrently with other cholinesterase inhibitors or cholinergic agonists.
MANAGEMENT: Monitoring for excessive cholinergic effects and seizure activity is recommended. Patients should be advised to notify their physician if they experience nausea, vomiting, diarrhea, abdominal pain, increased salivation, cold sweats, slow or irregular heartbeat, muscle weakness or cramps, dizziness, headache, seizures, or respiratory distress.
- "Product Information. Reminyl (galantamine)" Janssen Pharmaceuticals, Titusville, NJ.
- "Product Information. Aricept (donepezil)." Pfizer US Pharmaceuticals, New York, NY.
- "Product Information. Cognex (tacrine)." Parke-Davis, Morris Plains, NJ.
Generic Name: donepezil
Brand name: Aricept, Aricept ODT
Synonyms: Aricept
Generic Name: neostigmine
Brand name: Prostigmin, Bloxiverz
Synonyms: Neostigmine Tablets, Neostigmine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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