Aripiprazole, ARIPiprazole Lauroxil and Pexidartinib

• Generic Name: aripiprazole
• Dosage Forms: n.a.
• Other Brand Names: Abilify, Abilify Discmelt, Abilify Maintena, Aristada, Abilify MyCite, Aristada Initio

Used orally (as aripiprazole) and IM (as extended-release aripiprazole or aripiprazole lauroxil injection) for treatment of schizophrenia.

American Psychiatric Association (APA) considers most atypical antipsychotic agents first-line drugs for the management of the acute phase of schizophrenia (including first psychotic episodes).

Patients who do not respond to or tolerate one drug may be successfully treated with an agent from a different class or with a different adverse effect profile.

Immediate-release aripiprazole injection (no longer commercially available in the US) has been used IM for acute management of agitation in patients with schizophrenia.

Used orally alone or in conjunction with lithium or valproate for acute treatment of manic and mixed episodes associated with bipolar I disorder with or without psychotic features. Also used orally as monotherapy or as adjunctive therapy with lithium or valproate for maintenance treatment of bipolar I disorder.

Used IM (as extended-release aripiprazole injection [Abilify Maintena]) as monotherapy for maintenance treatment of bipolar I disorder.

Immediate-release aripiprazole injection (no longer commercially available in the US) has been used IM for acute management of agitation in patients with bipolar I disorder.

Used orally as adjunctive therapy to antidepressants for treatment of major depressive disorder.

Used orally for acute treatment of irritability associated with autistic disorder.

Used orally for treatment of Tourette's syndrome (Gilles de la Tourette’s syndrome).

• Generic Name: pexidartinib
• Dosage Forms: n.a.
• Other Brand Names: Turalio

• It is used to treat a type of cancer called tenosynovial giant cell tumor (TGCT).