Aristada Initio and Fluticasone Propionate

• Generic Name: aripiprazole
• Dosage Forms: injection, suspension, extended release
• Other Brand Names: Aristada, Aristada Initio, Abilify, Abilify Discmelt, Abilify Maintena, Abilify MyCite

• It is used to treat schizophrenia.

• Generic Name: fluticasone
• Dosage Forms: n.a.
• Other Brand Names: ArmonAir RespiClick 113, Arnuity Ellipta, Flovent Diskus, Flovent HFA, Flovent, Flovent Rotadisk, ArmonAir RespiClick 55, ArmonAir RespiClick 232

Fluticasone used for long-term prevention of bronchospasm in patients with asthma.

In corticosteroid-dependent patients, fluticasone may permit a substantial reduction in the daily maintenance dosage of the systemic corticosteroid and gradual discontinuance of corticosteroid maintenance dosages.

Fluticasone/salmeterol fixed combination is used only in patients with asthma not responding adequately to long-term asthma controller therapy (e.g., inhaled corticosteroids) or whose disease severity clearly warrants initiation of treatment with both an inhaled corticosteroid and a long-acting β2-adrenergic agonist.

Once asthma control achieved and maintained, assess patient at regular intervals and step down therapy (e.g., discontinue fluticasone/salmeterol), if possible without loss of asthma control, and maintain patient on long-term asthma controller therapy (e.g., inhaled corticosteroids).

Do not use fluticasone/salmeterol in patients with asthma adequately controlled on low or medium dosage of inhaled corticosteroids.

Fixed combination with salmeterol as the oral inhalation powder (Advair Diskus) is used for maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and/or emphysema; also used to reduce exacerbations of COPD in patients with a history of exacerbations.

Fluticasone/salmeterol is not indicated for relief of acute bronchospasm.