Asenapine Maleate and Siltuximab

• Generic Name: asenapine
• Dosage Forms: n.a.
• Other Brand Names: Saphris, Saphris Black Cherry

Acute and maintenance treatment of schizophrenia in adults.

American Psychiatric Association (APA) considers most atypical antipsychotic agents first-line drugs for management of the acute phase of schizophrenia (including first psychotic episodes).

Patients who do not respond to or tolerate one drug may be successfully treated with an agent from a different class or with a different adverse effect profile.

Acute treatment as monotherapy or adjunctive therapy with lithium or valproate of manic or mixed episodes associated with bipolar I disorder (with or without psychotic features).

Maintenance treatment as monotherapy of bipolar I disorder.

• Generic Name: siltuximab
• Dosage Forms: n.a.
• Other Brand Names: Sylvant

Siltuximab is used to treat Multicentric Castleman's Disease (MCD). MCD is a rare condition in which the body produces too much of a certain type of white blood cell. MCD can increase your risk of certain cancers by changing the way your immune system works.

Siltuximab is not for use in people who have human immunodeficiency virus (HIV) or human herpesvirus-8.

Siltuximab may also be used for purposes not listed in this medication guide.