Asenapine Maleate and Simvastatin

• Generic Name: asenapine
• Dosage Forms: n.a.
• Other Brand Names: Saphris, Saphris Black Cherry

Acute and maintenance treatment of schizophrenia in adults.

American Psychiatric Association (APA) considers most atypical antipsychotic agents first-line drugs for management of the acute phase of schizophrenia (including first psychotic episodes).

Patients who do not respond to or tolerate one drug may be successfully treated with an agent from a different class or with a different adverse effect profile.

Acute treatment as monotherapy or adjunctive therapy with lithium or valproate of manic or mixed episodes associated with bipolar I disorder (with or without psychotic features).

Maintenance treatment as monotherapy of bipolar I disorder.

• Generic Name: simvastatin
• Dosage Forms: n.a.
• Other Brand Names: Zocor, Flolipid

Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Simvastatin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Simvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.

Simvastatin is used in adults and children who are at least 10 years old.