Asparaginase and Depo-Provera (Medroxyprogesterone Injection (400 mg/mL))
Determining the interaction of Asparaginase and Depo-Provera (Medroxyprogesterone Injection (400 mg/mL)) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Theoretically, there is potential for an indirect interaction between asparaginase and oral contraceptives. The mechanism may involve asparaginase's hepatotoxicity, which may impair oral contraceptives' hepatic clearance. MANAGEMENT: The use of oral contraceptives during asparaginase treatment is not recommended. Other non-oral contraceptive methods should be used in women of childbearing potential. According to the manufacturer, females of reproductive potential should be advised to use effective contraception during asparaginase treatment and for at least 3 to 6 months after the last dose. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 Cerner Multum, Inc. "Australian Product Information." O 0 "Product Information. Asparlas (calaspargase pegol)." Servier, Boston, MA.
Professional:GENERALLY AVOID: Theoretically, there is potential for an indirect interaction between asparaginase and oral contraceptives. The mechanism may involve asparaginase's hepatotoxicity, which may impair oral contraceptives' hepatic clearance.
MANAGEMENT: The use of oral contraceptives during asparaginase treatment is not recommended. Other non-oral contraceptive methods should be used in women of childbearing potential. According to the manufacturer, females of reproductive potential should be advised to use effective contraception during asparaginase treatment and for at least 3 to 6 months after the last dose.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Asparlas (calaspargase pegol)." Servier, Boston, MA.
Generic Name: asparaginase escherichia coli
Brand name:
Synonyms: Asparaginase (E. coli)
Generic Name: medroxyprogesterone
Brand name: Provera, Depo-Provera, Depo-subQ provera 104, Depo-Provera Contraceptive
Synonyms: Medroxyprogesterone, MedroxyPROGESTERone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Asparaginase-Depo-Provera (Medroxyprogesterone Injection (Intramuscular))
- Asparaginase-Depo-Provera Contraceptive
- Asparaginase-Depo-Provera Contraceptive injection
- Asparaginase-Depo-Provera injection
- Asparaginase-Depo-subQ provera 104
- Asparaginase-Depo-SubQ Provera 104 injection
- Depo-Provera (Medroxyprogesterone Injection (400 mg/mL))-Asparaginase (E. coli)
- Depo-Provera (Medroxyprogesterone Injection (400 mg/mL))-Asparaginase (Erwinia)
- Depo-Provera (Medroxyprogesterone Injection (400 mg/mL))-Asparaginase Erwinia chrysanthemi
- Depo-Provera (Medroxyprogesterone Injection (400 mg/mL))-Asparaginase erwinia chrysanthemi Intramuscular
- Depo-Provera (Medroxyprogesterone Injection (400 mg/mL))-Asparlas
- Depo-Provera (Medroxyprogesterone Injection (400 mg/mL))-Aspercreme Lidocaine