Aspirin and Diphenhydramine and No Doz Maximum Strength
Determining the interaction of Aspirin and Diphenhydramine and No Doz Maximum Strength and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study has reported that coadministration of caffeine and aspirin lead to a 25% increase in the rate of appearance and 17% increase in maximum concentration of salicylate in the plasma. A significantly higher area under the plasma concentration time curve of salicylate was also reported when both drugs were administered together. The exact mechanism of this interaction has not been specified. Physicians and patients should be aware that coadministration of aspirin and caffeine may lead to higher salicylate levels faster.
- Yoovathaworn KC, Sriwatanakul K, Thithapandha A "Influence of caffeine on aspirin pharmacokinetics." Eur J Drug Metab Pharmacokinet 11 (1986): 71-6
Generic Name: aspirin / diphenhydramine
Brand name: Bayer PM
Synonyms: n.a.
Generic Name: caffeine
Brand name: Cafcit, NoDoz, Vivarin
Synonyms: No Doz Maximum Strength (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aspirin and Diphenhydramine-Nocdurna
- Aspirin and Diphenhydramine-Noctiva
- Aspirin and Diphenhydramine-Noctiva nasal
- Aspirin and Diphenhydramine-Nodolor
- Aspirin and Diphenhydramine-Nodolor Capsules
- Aspirin and Diphenhydramine-NoDoz
- No Doz Maximum Strength-Aspirin and dipyridamole
- No Doz Maximum Strength-Aspirin and Dipyridamole Capsules
- No Doz Maximum Strength-Aspirin and omeprazole
- No Doz Maximum Strength-Aspirin and Omeprazole Tablets
- No Doz Maximum Strength-Aspirin and oxycodone
- No Doz Maximum Strength-Aspirin Chewable Tablets