Aspirin, butalbital, and caffeine and Busulfan

• Generic Name: aspirin / butalbital / caffeine
• Dosage Forms: n.a.
• Other Brand Names: Butalbital Compound, Fiorinal, Fiormor, Fiortal, Fortabs, Idenal, Laniroif

Aspirin is a pain reliever, as well as an anti-inflammatory and a fever reducer.

Butalbital is a barbiturate. It relaxes muscle contractions involved in a tension headache.

Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Aspirin, butalbital, and caffeine is a combination medicine used to treat tension headaches. aspirin, butalbital, and caffeine is not for treating headaches that come and go.

Aspirin, butalbital, and caffeine may also be used for purposes not those listed in this medication guide.

• Generic Name: busulfan
• Dosage Forms: n.a.
• Other Brand Names: Busulfex, Myleran

Used IV in combination with cyclophosphamide: as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation in patients with chronic myelogenous leukemia (CML) (designated an orphan drug by US FDA for this use).

Also administered orally as a component of a conditioning regimen prior to allogeneic transplantation.

Rarely, used as an alternative agent for palliative treatment of CML. Not curative, but approximately 90% of patients in the chronic phase of CML treated with the drug obtain remissions.

Component of pretransplant conditioning regimens in patients undergoing bone marrow transplantation for acute myeloid leukemia and nonmalignant diseases (e.g., sickle cell disease).