Aspirin, chlorpheniramine, and phenylephrine and DDAVP
Determining the interaction of Aspirin, chlorpheniramine, and phenylephrine and DDAVP and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data have shown that desmopressin (DDAVP) can significantly reduce aspirin-induced increases in bleeding times. The DDAVP effect on bleeding time correlates closely with increases in the plasma concentration of von Willebrand factor. The clinical consequences of this interaction are not known.
- Beck KH, Mohr P, Bleckmann U, Schweer H, Kretschmer V "Desmopressin effect on acetylsalicylic acid impaired platelet function." Semin Thromb Hemost 21 Suppl (1995): 32-9
Generic Name: aspirin / chlorpheniramine / phenylephrine
Brand name: Alka-Seltzer Plus Cold Formula
Synonyms: n.a.
Generic Name: desmopressin
Brand name: DDAVP, Nocdurna, DDAVP nasal, DDAVP Rhinal Tube, Noctiva, Stimate
Synonyms: DDAVP (injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aspirin, chlorpheniramine, and phenylephrine-DDAVP (Desmopressin Injection Solution)
- Aspirin, chlorpheniramine, and phenylephrine-DDAVP (Desmopressin Nasal Spray (Diabetes Insipidus))
- Aspirin, chlorpheniramine, and phenylephrine-DDAVP (Desmopressin Tablets)
- Aspirin, chlorpheniramine, and phenylephrine-DDAVP injection
- Aspirin, chlorpheniramine, and phenylephrine-DDAVP nasal
- Aspirin, chlorpheniramine, and phenylephrine-DDAVP Nasal Spray
- DDAVP-Aspirin, Citric Acid, and Sodium Bicarbonate
- DDAVP-Aspirin, Salicylamide, and Caffeine
- DDAVP-Aspirin, sodium bicarbonate, and citric acid
- DDAVP-Aspiritab
- DDAVP-Aspirtab
- DDAVP-Astagraf XL