Astelin and Collagenase clostridium histolyticum

• Generic Name: azelastine nasal
• Dosage Forms: nasal spray, metered
• Other Brand Names: Astelin, Astepro

Astelin (azelastine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Astelin nasal spray is used to treat sneezing, runny or stuffy nose, itching, and other nasal symptoms of allergies, in adults and children who are at least 5 years old.

Astelin is also used to treat ongoing nasal symptoms (runny or stuffy nose, sneezing, itching) that are not caused by allergies, in adults and children who are at least 12 years old.

• Generic Name: collagenase clostridium histolyticum
• Dosage Forms: n.a.
• Other Brand Names: Xiaflex

Collagenase clostridium histolyticum is made from a mixture of proteins derived from a certain bacteria.

Collagenase clostridium histolyticum is used to treat Dupuytren's contracture in adults. This condition causes an abnormal thickening of the tissue in the palm of the hand. This condition may get worse over time and form a "cord" in your palm, causing a permanent bend in your finger.

Collagenase clostridium histolyticum is also used to treat a related condition called Peyronie's disease in adult men. This condition causes scar tissue or "plaque" to develop under the skin of the penis, resulting in an abnormal curving of the penis during erection.

Collagenase clostridium histolyticum is available for Peyronie's disease only from a certified pharmacy under a special program called Xiaflex REMS. You must be registered in the program and understand the risks of taking collagenase clostridium histolyticum.

Collagenase clostridium histolyticum may also be used for purposes not listed in this medication guide.