Atazanavir Powder for Oral Suspension and Isentress (Raltegravir Chewable Tablets)
Determining the interaction of Atazanavir Powder for Oral Suspension and Isentress (Raltegravir Chewable Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with inhibitors of uridine diphosphate glucuronosyltransferase (UGT) 1A1 such as atazanavir, nilotinib, or sorafenib may increase the plasma concentrations of raltegravir, which is primarily metabolized by UGT1A1-mediated glucuronidation. However, concurrent use of atazanavir/ritonavir in clinical trials did not result in meaningful differences in the safety of raltegravir. Based on these data, no dosage adjustment of raltegravir is necessary when used together with atazanavir/ritonavir or other UGT1A1 inhibitors.
- "Product Information. Isentress (raltegravir)." Merck & Company Inc, West Point, PA.
Generic Name: atazanavir
Brand name: Reyataz
Synonyms: Atazanavir
Generic Name: raltegravir
Brand name: Isentress, Isentress HD
Synonyms: Isentress
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Atazanavir Powder for Oral Suspension-Isentress (Raltegravir Powder for Oral Suspension)
- Atazanavir Powder for Oral Suspension-Isentress (Raltegravir Tablets)
- Atazanavir Powder for Oral Suspension-Isentress HD
- Atazanavir Powder for Oral Suspension-Isibloom
- Atazanavir Powder for Oral Suspension-Ismelin
- Atazanavir Powder for Oral Suspension-ISMO
- Isentress (Raltegravir Chewable Tablets)-Atazanavir Sulfate
- Isentress (Raltegravir Chewable Tablets)-Atelvia
- Isentress (Raltegravir Chewable Tablets)-Atendia Patch
- Isentress (Raltegravir Chewable Tablets)-Atenolol
- Isentress (Raltegravir Chewable Tablets)-Atenolol and chlorthalidone
- Isentress (Raltegravir Chewable Tablets)-Atenolol and Chlorthalidone Tablets