Atenolol and chlorthalidone and Bavencio

• Generic Name: atenolol / chlorthalidone
• Dosage Forms: n.a.
• Other Brand Names: Tenoretic 100, Tenoretic 50, Tenoretic

Atenolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Atenolol and chlorthalidone is a combination medicine used to treat hypertension (high blood pressure). Lowering blood pressure may lower your risk of a stroke or heart attack.

Atenolol and chlorthalidone may also be used for purposes not listed in this medication guide.

• Generic Name: avelumab
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Bavencio

Bavencio (avelumab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Bavencio is used to treat a type of skin cancer called Merkel cell carcinoma (MCC) in adults and children at least 12 years old, when the cancer has spread to other parts of the body (metastatic).

Bavencio was approved for MCC by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, tumors responded to this medicine. However, further studies are needed.

Bavencio is used to treat a certain type of cancer of the bladder or urinary tract that has spread or cannot be removed with surgery. Avelumab is given for this condition after platinum cancer medicines did not work or have stopped working.

Bavencio is also used used alone or in combination with the medicine axitinib for the treatment of a type of kidney cancer called renal cell carcinoma (RCC) that has spread or cannot be removed by surgery (advanced RCC).