Ativan and Quetiapine

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Before using LORazepam, tell your doctor if you also use QUEtiapine. This combination may cause excessive sedation, confusion, dizziness, or lack of coordination. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: The oral clearance of a single dose of lorazepam has been reported to be decreased by 20% when taken concomitantly with quetiapine. The mechanism of the interaction is unknown. Additionally, quetiapine may enhance the CNS effects of lorazepam.

MANAGEMENT: The clinician may consider closer clinical monitoring of the patient for lorazepam toxicity if quetiapine and lorazepam are coadministered. Patients should be advised to notify their physician if they experience symptoms such as excessive sedation, confusion, dizziness, or incoordination.

Ativan

Generic Name: lorazepam

Brand name: Ativan, Lorazepam Intensol

Synonyms: n.a.

What is Ativan?

Quetiapine

Generic Name: quetiapine

Brand name: Seroquel, Seroquel XR

Synonyms: QUEtiapine

What is Quetiapine?