ATNAA and Pramipexole ER Tablets

• Generic Name: atropine / pralidoxime
• Dosage Forms: injection
• Other Brand Names: ATNAA, DuoDote

Atropine blocks the action of a certain chemical that may reach high levels in the body after a poisoning. Atropine also stimulates the heart and reduces the secretions of the nose, mouth, and lungs to improve breathing.

Pralidoxime reverses muscle weakness or paralysis caused by a poison or nerve agent.

ATNAA is a combination medicine used as an antidote to treat poisoning by a pesticide (insect spray) or a chemical that interferes with the central nervous system, such as nerve gas.

ATNAA is not effective as an antidote for all types of pesticide poisonings. You may need medications or additional treatments.

ATNAA may also be used for purposes not listed in this medication guide.

• Generic Name: pramipexole
• Dosage Forms: tablet, extended release
• Other Brand Names: Mirapex, Mirapex ER

Symptomatic management of idiopathic parkinsonian syndrome.

Used as an adjunct to levodopa for the symptomatic management of parkinsonian syndrome in patients with advanced disease.

Also used as monotherapy for the initial symptomatic management of parkinsonian syndrome. Most clinicians would use levodopa for initial therapy in individuals >70 years of age (less likely than younger individuals to develop levodopa-related motor complications and because of concerns about cognitive dysfunction), in patients with cognitive impairment, and in those with severe disease. A dopamine receptor agonist may be preferred for initial therapy in patients ≤70 years of age.

Symptomatic management of moderate-to-severe primary restless legs syndrome (Ekbom syndrome).