Atorvastatin Calcium and Ortho-Novum 7/7/7 birth control
Determining the interaction of Atorvastatin Calcium and Ortho-Novum 7/7/7 birth control and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with atorvastatin may increase the plasma concentrations of estrogens and progestins. The exact mechanism of interaction is unknown but may be related to competitive inhibition of CYP450 3A4, the isoenzyme responsible for the metabolism of atorvastatin, estrogens, some (if not all) progestins, and other steroids. According to product labeling, atorvastatin increased the area under the plasma concentration-time curve (AUC) of ethinyl estradiol by 20% and that of norethindrone by 30%. The clinical significance of these alterations is unknown but should be considered when selecting oral contraceptive and hormone replacement doses.
- "Product Information. Lipitor (atorvastatin)." Parke-Davis, Morris Plains, NJ.
Generic Name: atorvastatin
Brand name: Lipitor
Synonyms: Atorvastatin, AtorvaSTATin
Generic Name: ethinyl estradiol / norethindrone
Brand name: Blisovi 24 Fe, Brevicon, Estrostep Fe, Femcon Fe, Kaitlib FE, Lo Minastrin Fe, Loestrin 24 Fe, Microgestin 24 Fe, Norinyl 1+35, Ortho-Novum 7/7/7, Taytulla, Tri-Norinyl, Zenchent, Blisovi 24 Fe, Blisovi Fe 15/30, Blisovi Fe 1/20, Gildess 24 Fe, Gildess Fe 15/30, Gildess Fe 1/20, Junel Fe 15/30, Junel Fe 1/20, Junel Fe 24, Larin 24 Fe, Larin Fe 15/30, Larin Fe 1/20, Lo Loestrin Fe, Loestrin Fe 15/30, Loestrin Fe 1/20, Lomedia 24 Fe, Microgestin 24 Fe, Microgestin Fe 15/30, Microgestin Fe 1/20, Tarina Fe 1/20, Tilia Fe, Tri-Legest Fe, femhrt 05 mg/25 mcg, Fyavolv, Jevantique Lo, Jinteli, Femcon Fe, Generess FE, Loestrin 1/20, Ovcon 35
Synonyms: Ortho-Novum 7/7/7, Ortho-Novum 777
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Atorvastatin Calcium-Orthoclone OKT 3
- Atorvastatin Calcium-Orthovisc
- Atorvastatin Calcium-Orudis
- Atorvastatin Calcium-Orudis KT
- Atorvastatin Calcium-Oruvail
- Atorvastatin Calcium-Orvaten
- Ortho-Novum 7/7/7 birth control-Atovaquone
- Ortho-Novum 7/7/7 birth control-Atovaquone and proguanil
- Ortho-Novum 7/7/7 birth control-Atovaquone and Proguanil Hydrochloride
- Ortho-Novum 7/7/7 birth control-Atovaquone Suspension
- Ortho-Novum 7/7/7 birth control-Atracurium
- Ortho-Novum 7/7/7 birth control-Atracurium Besylate