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Atovaquone and Didanosine Tablet, for suspension

Determining the interaction of Atovaquone and Didanosine Tablet, for suspension and the possibility of their joint administration.

Check result:

Atovaquone <> Didanosine Tablet, for suspension

Relevance: 09.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with atovaquone has been shown to decrease the systemic exposure (AUC) of didanosine by 24% in a multi-dose drug interaction study. The mechanism is unknown, although the interaction is unlikely to be of clinical significance. Didanosine had no effect on the pharmacokinetics of atovaquone.

References

"Product Information. Mepron (atovaquone)." Glaxo Wellcome, Research Triangle Park, NC.

Atovaquone

Generic Name: atovaquone

Brand name: Mepron

Synonyms: n.a.

What is Atovaquone?

Didanosine Tablet, for suspension

Generic Name: didanosine

Brand name: Videx, Videx EC

Synonyms: Didanosine

What is Didanosine Tablet, for suspension?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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