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Atovaquone and proguanil and Calcium Carbonate Capsules and Tablets

Determining the interaction of Atovaquone and proguanil and Calcium Carbonate Capsules and Tablets and the possibility of their joint administration.

Check result:
Atovaquone and proguanil <> Calcium Carbonate Capsules and Tablets
Relevance: 28.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using calcium carbonate together with proguanil can decrease the effects of proguanil. Calcium carbonate and proguanil should be taken at least 2 to 3 hours apart. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: The concomitant administration of magnesium trisilicate may significantly reduce the bioavailability of proguanil by reducing its absorption. Therapeutic failure may result. Other antacids and absorbent antidiarrheals may also interact with proguanil.

MANAGEMENT: Antacids or antidiarrheals and proguanil should be taken at least 2 to 3 hours apart.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Multum Information Services, Inc. Expert Review Panel"
Atovaquone and proguanil

Generic Name: atovaquone / proguanil

Brand name: Malarone, Malarone Pediatric

Synonyms: Atovaquone and Proguanil

Calcium Carbonate Capsules and Tablets

Generic Name: calcium carbonate

Brand name: Calci-Chew, Oysco 500, Calci Mix, Os-Cal 500, Oyst Cal 500, Oyster Shell Calcium 500, Nephro Calci, Amitone, Dicarbosil, Equilet, Tums, Chooz, Tums E-X, Alkets, Titralac, Oyster Cal 500, Calcitab, Oyster Shell, Oyster Calcium, Super Calcium, Calcium Concentrate, Caltro, Oyster, Oyster Cal, Cal Oys, Alkums, Cal-Gest, Tums 500, Tums Ultra, Alka-Mints, Calcarb, Caltrate, Rolaids Sodium Free, Amilac, Calcium Oyster, Oyst Cal, Calcium Liquid Softgel, Mylanta Child, Maalox Quick Dissolve, Maalox Quick Dissolve Maximum Strength, Ultra Mylanta Calci Tabs, Extra Strength Mylanta Calci Tabs, Os-Cal, Surpass, Surpass Extra Strength, Icar Prenatal Chewable Calcium, Tums Extra Strength, Maalox Quick Dissolve Extra Strength, Calcium Oyster Shell, Maalox Antacid Barrier, Rolaids Soft Chew, Pepto Children's, Maalox Regular Strength, Maalox Children's, Tums Kids, Tums QuikPak, Calci-Mix, Alcalak, Tums Smoothies, Tums Chewy Bites, Tums Chewy Delights, Tums Sugar-Free, Cal-Mint, Calci Mix, OsCal 500

Synonyms: Calcium carbonate, Calcium Carbonate

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.