Atovaquone and proguanil and Sodium Bicarbonate Infant Injection

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using sodium bicarbonate together with proguanil can decrease the effects of proguanil. Sodium bicarbonate and proguanil should be taken at least 2 to 3 hours apart. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: The concomitant administration of magnesium trisilicate may significantly reduce the bioavailability of proguanil by reducing its absorption. Therapeutic failure may result. Other antacids and absorbent antidiarrheals may also interact with proguanil.

MANAGEMENT: Antacids or antidiarrheals and proguanil should be taken at least 2 to 3 hours apart.

Atovaquone and proguanil

Generic Name: atovaquone / proguanil

Brand name: Malarone, Malarone Pediatric

Synonyms: Atovaquone and Proguanil

What is Atovaquone and proguanil?

Sodium Bicarbonate Infant Injection

Generic Name: sodium bicarbonate

Brand name: Neut

Synonyms: Sodium bicarbonate, Sodium Bicarbonate

What is Sodium Bicarbonate Infant Injection?