Atracurium and Carbamazepine Extended-Release Capsules (Carbatrol)
Determining the interaction of Atracurium and Carbamazepine Extended-Release Capsules (Carbatrol) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using carBAMazepine together with atracurium may decrease the effects of atracurium. Close observation is recommended if you are using both medications. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Carbamazepine may reduce the effects or duration of nondepolarizing neuromuscular blocking agents. The mechanism is unknown.
MANAGEMENT: Close observation for decreased neuromuscular blocking effect is recommended if a patient on carbamazepine must receive a nondepolarizing neuromuscular blocking agent.
- Roth S, Ebrahim ZY "Resistance to pancuronium in patients receiving carbamazepine." Anesthesiology 66 (1987): 691-3
- Tempelhoff R, Modica PA, Jellish WS, Spitznagel EL "Resistance to atracurium-induced neuromuscular blockade in patients with intractable seizure disorders treated with anticonvulsants." Anesth Analg 71 (1990): 665-9
- Whalley DG, Ebrahim Z "Influence of carbamazepine on the dose-response relationship of vecuronium." Br J Anaesth 72 (1994): 125-6
- Norman J "Resistance to vecuronium." Anaesthesia 48 (1993): 1068-9
Generic Name: carbamazepine
Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR
Synonyms: Carbamazepine, CarBAMazepine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Atracurium-Carbamazepine Extended-Release Capsules (Equetro)
- Atracurium-Carbamazepine Extended-Release Tablets
- Atracurium-Carbamazepine Intravenous
- Atracurium-Carbamazepine Oral Suspension
- Atracurium-Carbamazepine Tablets
- Atracurium-Carbaphen 12
- Carbamazepine Extended-Release Capsules (Carbatrol)-Atracurium Besylate
- Carbamazepine Extended-Release Capsules (Carbatrol)-Atracurium Besylate Injection
- Carbamazepine Extended-Release Capsules (Carbatrol)-Atralin
- Carbamazepine Extended-Release Capsules (Carbatrol)-Atralin Gel
- Carbamazepine Extended-Release Capsules (Carbatrol)-Atralin Topical
- Carbamazepine Extended-Release Capsules (Carbatrol)-Atridox