AtroPen and Protopam Chloride
Determining the interaction of AtroPen and Protopam Chloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Pralidoxime and other drugs within the family of compounds called oximes, such as obidoxime, may potentiate the pharmacologic effects of atropine. Signs of atropinization such as flushing, mydriasis, tachycardia, and dry mouth and nose may occur earlier than expected during coadministration with pralidoxime relative to administration of atropine alone, particularly if the total dose of atropine has been large and the administration of pralidoxime was delayed. Clinicians should be aware of the potential interaction and monitor patients as appropriate. Pralidoxime may be used in conjunction with atropine in the treatment of organophosphate insecticide poisoning and nerve agent poisoning in terrorism or chemical warfare.
- "Product Information. DuoDote (atropine-pralidoxime)." Meridian Medical Technologies Inc, Columbia, MD.
Generic Name: atropine
Brand name: AtroPen, Sal-Tropine, Atreza
Synonyms: n.a.
Generic Name: pralidoxime
Brand name: Protopam Chloride
Synonyms: Protopam
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- AtroPen-Protophylline Alcohol And Sugar Free
- AtroPen-Protriptyline
- AtroPen-Protriptyline Hydrochloride
- AtroPen-Protyl Ag
- AtroPen-ProvayBlue
- AtroPen-Provayblue injection
- Protopam Chloride-Atropin-Care
- Protopam Chloride-Atropine (Systemic)
- Protopam Chloride-Atropine and diphenoxylate
- Protopam Chloride-Atropine and pralidoxime
- Protopam Chloride-Atropine Auto-Injector
- Protopam Chloride-Atropine Care Ophthalmic