Atropine Sulfate eent and Methscopolamine Bromide

• Generic Name: atropine ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Atropine-1, Isopto Atropine, Atropisol, Ocu-Tropine, Atropine Care, Atrosulf-1, Atropin-Care

Used to produce mydriasis and cycloplegia for refraction (e.g., retina and optic disc examination, measurement of refractive error). However, because of long duration of action relative to that of other anticholinergic agents, atropine is seldom, if ever, used for cycloplegic refraction in adults.

In rare cases, ophthalmic atropine use may be necessary to achieve maximal cycloplegia in pediatric patients, but cyclopentolate is more frequently used.

Management of acute inflammatory conditions (e.g., iridocyclitis) of the iris and uveal tract (e.g., uveitis).

Used for cycloplegic effects in the treatment of suppression amblyopia (lazy eye) to reduce the visual acuity of the unaffected eye below that of the amblyopic one and force fixation with the amblyopic eye.

Used to treat patients with a functional excess of accommodation and convergence.

• Generic Name: methscopolamine
• Dosage Forms: n.a.
• Other Brand Names: Pamine, Pamine Forte

Adjunctive therapy in the treatment of peptic ulcer disease; however, no conclusive data that antimuscarinics aid in the healing, decrease the rate of recurrence, or prevent complications of peptic ulcers.

With the advent of more effective therapies for the treatment of peptic ulcer disease, antimuscarinics have only limited usefulness in this condition.