Atropine sulfate Ophthalmic and Irinotecan Hydrochloride

• Generic Name: atropine ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Atropine-1, Isopto Atropine, Atropisol, Ocu-Tropine, Atropine Care, Atrosulf-1, Atropin-Care

Atropine sulfate eye drops is used to dilate the pupil before eye exams. It is also used to treat an eye condition called amblyopia (lazy eyes) and other eye conditions (eg, cycloplegia). Atropine sulfate works by blocking the chemical acetylcholine, which relaxes the ciliary muscle of the eye and causes the pupil to dilate.

Atropine sulfate is available only with your doctor's prescription.

• Generic Name: irinotecan
• Dosage Forms: n.a.
• Other Brand Names: Camptosar

Conventional irinotecan: Used as a component of first-line therapy in combination with fluorouracil and leucovorin for the treatment of metastatic carcinoma of the colon or rectum.

Conventional irinotecan: Used as a single agent for treatment of metastatic carcinoma of the colon or rectum in patients whose disease has recurred or progressed following initial therapy with fluorouracil-based antineoplastic regimens.

Liposomal irinotecan: Used in combination with fluorouracil and leucovorin for the treatment of metastatic adenocarcinoma of the pancreas in patients whose disease has progressed following gemcitabine-based chemotherapy (designated an orphan drug by FDA for treatment of this cancer ).

Conventional irinotecan: Used in combination with cisplatin for the initial treatment of extensive small cell lung cancer.

Conventional irinotecan: Under investigation for the treatment of metastatic or recurrent cervical cancer.