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Aubagio and Cipro Iv Minibags

Determining the interaction of Aubagio and Cipro Iv Minibags and the possibility of their joint administration.

Check result:

Aubagio <> Cipro Iv Minibags

Relevance: 28.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Teriflunomide may increase the blood levels and effects of ciprofloxacin. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration with teriflunomide may increase the plasma concentrations and the risk of adverse effects of drugs that are substrates of organic anion transporter 3 (OAT3). The proposed mechanism, based on in vivo data, is decreased clearance due to teriflunomide-mediated inhibition of OAT3 transporter. Following repeated doses of teriflunomide, the mean Cmax and AUC of cefaclor, an OAT3 substrate, increased 1.43- and 1.54-fold, respectively.

MANAGEMENT: Caution is advised if teriflunomide is used concomitantly with drugs that are substrates of OAT3. Dosage adjustments as well as clinical and laboratory monitoring should be considered whenever teriflunomide is added to or withdrawn from therapy with these drugs. Patients should be monitored for the development of adverse effects.

References

"Product Information. Aubagio (teriflunomide)." Genzyme Corporation, Cambridge, MA.
Cerner Multum, Inc. "Australian Product Information." O 0
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Aubagio

Generic Name: teriflunomide

Brand name: Aubagio

Synonyms: n.a.

What is Aubagio?

Cipro Iv Minibags

Generic Name: ciprofloxacin

Brand name: Cipro IV, Cipro, Cipro XR, Proquin XR

Synonyms: Cipro I.V. (injection)

What is Cipro Iv Minibags?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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