Drug search by name

Avelox and Bacillus of calmette and guerin vaccine, live Intravesical

Determining the interaction of Avelox and Bacillus of calmette and guerin vaccine, live Intravesical and the possibility of their joint administration.

Check result:

Avelox <> Bacillus of calmette and guerin vaccine, live Intravesical

Relevance: 17.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using BCG together with moxifloxacin is not recommended. Medications that are used to treat tuberculosis such as moxifloxacin may reduce the anti-tumor activity of BCG in the bladder. In addition, if you have active tuberculosis, you should not receive treatment with BCG. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Antituberculosis drugs may interfere with the anti-tumor activity of intravesical BCG, which contains a live, attenuated strain of Mycobacterium bovis. Available data suggest that intravesical BCG may be sensitive to most antibiotics, particularly those that are routinely used in the treatment of tuberculosis such as streptomycin, para-aminosalicylic acid (PAS), isoniazid (INH), rifampin, and ethambutol. It is reportedly not sensitive to pyrazinamide or cycloserine. Regardless of clinical susceptibility data, however, most antibacterials may still interfere with BCG in the bladder due to their high urinary recovery.

MANAGEMENT: Concomitant use of antituberculosis drugs is considered contraindicated during intravesical BCG therapy. Moreover, intravesical BCG should not be used in patients with active tuberculosis. If persistent fever develops or an acute febrile illness consistent with BCG infection occurs during intravesical BCG therapy, the medication should be permanently discontinued and the patient immediately evaluated and treated for BCG infection. An infectious disease consultation should be sought in determining the appropriate treatment. There are no data to suggest that the acute, local urinary tract toxicity common with intravesical administration of BCG is due to mycobacterial infection, thus antituberculosis drugs should not be used to prevent or treat the local, irritative toxicities of intravesical BCG.

References

"Product Information. Tice BCG Live (for intravesical use) (BCG)." Organon Pharmaceuticals, West Orange, NJ.
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Durek C, Rusch-Gerdes S, Jocham D, Bohle A "Interference of modern antibacterials with bacillus Calmette-Guerin viability." J Urol 162 (1999): 1959-62
"Product Information. Tice BCG Vaccine (BCG (BCG vaccine))." Organon, West Orange, NJ.
Cerner Multum, Inc. "Australian Product Information." O 0

Avelox

Generic Name: moxifloxacin

Brand name: Avelox, Avelox IV

Synonyms: n.a.

What is Avelox?

Bacillus of calmette and guerin vaccine, live Intravesical

Generic Name: bcg

Brand name: Tice BCG Live, Tice BCG Vaccine, Theracys 3, TheraCys, BCG vaccine, Tice BCG

Synonyms: BCG intravesical, BCG (Intravesical)

What is Bacillus of calmette and guerin vaccine, live Intravesical?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions