Avonex Pen and Dipivefrin Hydrochloride

• Generic Name: interferon beta-1a
• Dosage Forms: n.a.
• Other Brand Names: Avonex, Avonex Pen, Rebif, Avonex Prefilled Syringe, Rebif Rebidose, Rebif Rebidose Titration Pack, Rebif Titration Pack

• It is used to treat MS (multiple sclerosis).

• Generic Name: dipivefrin ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Propine

Reduction of elevated IOP in patients with open-angle glaucoma. Used alone or in conjunction with other IOP-lowering drugs. May be used as initial therapy or for control of IOP in those patients who have not responded adequately to other antiglaucoma agents.

May be preferred as an alternative to topical epinephrine in some patients (e.g., those with cardiovascular disease) because of increased intraocular penetration (lower doses are needed) and resultant decreased adverse systemic effects (e.g., cardiovascular effects) compared with epinephrine.

Does not produce miosis, accommodative spasm, blurred vision, or night blindness. Less likely than epinephrine to cause adenochrome staining of contact lenses.

Has been used to reduce IOP in the treatment of other ocular conditions, including ocular hypertension and pseudoexfoliative, low-tension, and secondary (e.g., post-angle closure, pigmentary, traumatic, herpes zoster) glaucomas.