Axicabtagene ciloleucel Intravenous and Lenvatinib

• Generic Name: axicabtagene ciloleucel
• Dosage Forms: n.a.
• Other Brand Names: Yescarta

Axicabtagene ciloleucel injection is used to treat large B-cell lymphoma (including diffuse large B-cell lymphoma [DLBCL], primary mediastinal large B-cell lymphoma, high grade B-cell lymphoma, or DLBCL from follicular lymphoma) that has come back or after 2 or more lines of treatment did not work well.

Axicabtagene ciloleucel injection is an antineoplastic (cancer) medicine that is made from your own white blood cells, which have been modified to recognize and attack your cancer cells. Before you begin treatment, talk to your doctor about the benefits of axicabtagene ciloleucel as well as the possible risks of receiving it.

Axicabtagene ciloleucel is available only under a restricted distribution program called Yescarta™ REMS (Risk Evaluation and Mitigation Strategy) Program.

• Generic Name: lenvatinib
• Dosage Forms: n.a.
• Other Brand Names: Lenvima, Lenvima 8 mg daily-dose, Lenvima 20 mg daily-dose, Lenvima 12 mg daily-dose

Lenvatinib is used to treat thyroid cancer. Lenvatinib is usually given after radioactive iodine has been tried without success.

Lenvatinib is used together with everolimus (Afinitor) to treat advanced kidney cancer when other medicines have not been effective.

Lenvatinib is used together with pembrolizumab (Keytruda) to treat a certain type of endometrial cancer (a type of uterine cancer) that has progressed and cannot be removed with surgery or radiation.

Lenvatinib is also used to treat liver cancer that cannot be removed with surgery.

Lenvatinib may also be used for purposes not listed in this medication guide.