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Axid Oral Solution and Etravirine

Determining the interaction of Axid Oral Solution and Etravirine and the possibility of their joint administration.

Check result:
Axid Oral Solution <> Etravirine
Relevance: 16.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with ranitidine may slightly reduce the plasma concentrations of etravirine. The mechanism of interaction has not been described. In 18 study subjects administered etravirine with ranitidine 150 mg twice a day, etravirine peak plasma concentration (Cmax) and systemic exposure (AUC) decreased by 6% and 14%, respectively. These changes are not considered clinically significant. Etravirine and ranitidine may be coadministered without any dosage adjustments.

References
  • "Product Information. Intelence (etravirine)." Ortho Biotech Inc, Bridgewater, NJ.
Axid Oral Solution

Generic Name: nizatidine

Brand name: Baciguent, Probiotic Formula, Proferrin-ES

Synonyms: n.a.

Etravirine

Generic Name: etravirine

Brand name: Intelence

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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