Axid Oral Solution and Propulsid

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

During coadministration, cisapride may accelerate but slightly decrease the extent of gastrointestinal absorption of ranitidine. These effects are thought to be secondary to the increased gastrointestinal transit induced by cisapride. In twelve healthy volunteers given cisapride (10 mg single dose) and ranitidine (150 mg single dose), median time to reach peak plasma concentration (Tmax) of ranitidine was one hour less than when ranitidine was taken alone, and area under the concentration-time curve (AUC) was decreased by 24%. Theoretically, the reduced Tmax may translate to a quicker onset of action of ranitidine. The reduction in bioavailability is unlikely to be of clinical significance during regular administration, although the duration of action of a single dose of oral ranitidine may be shortened.

Axid Oral Solution

Generic Name: nizatidine

Brand name: Baciguent, Probiotic Formula, Proferrin-ES

Synonyms: n.a.

What is Axid Oral Solution?

Propulsid

Generic Name: cisapride

Brand name: Propulsid

Synonyms: Propulsid (Suspension)

What is Propulsid?