Azathioprine Injection and Rocuronium Bromide Injection
Determining the interaction of Azathioprine Injection and Rocuronium Bromide Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that azathioprine may variously enhance, reduce, or reverse the effects of neuromuscular blockers. The mechanism for enhancement of effects is unknown. The mechanism for reduction of effects may be related to inhibition of phosphodiesterase in motor nerve terminals. The clinical significance is unknown. Routine dose titration and standard monitoring of the patient are recommended.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Gramstad L "Atracurium, vecuronium and pancuronium in end-stage renal failure." Br J Anaesth 59 (1987): 995-1003
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Dretchen KL, Norgenroth VH, Standaert FG, Walts LF "Azathioprine: effects on neuromuscular transmission." Anesthesiology 45 (1976): 604-9
Generic Name: azathioprine
Brand name: Azasan, Imuran
Synonyms: Azathioprine, AzaTHIOprine
Generic Name: rocuronium
Brand name: Zemuron
Synonyms: Rocuronium
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Azathioprine Injection-Rocuronium Intravenous
- Azathioprine Injection-Rodex
- Azathioprine Injection-Roferon-A
- Azathioprine Injection-Roflumilast
- Azathioprine Injection-Roflumilast Tablets
- Azathioprine Injection-Rogaine
- Rocuronium Bromide Injection-Azathioprine Intravenous
- Rocuronium Bromide Injection-Azathioprine Oral, Intravenous
- Rocuronium Bromide Injection-Azathioprine Sodium
- Rocuronium Bromide Injection-Azathioprine Tablets
- Rocuronium Bromide Injection-Azedra
- Rocuronium Bromide Injection-Azedra Dosimetric