Azilsartan medoxomil and Garlic
Determining the interaction of Azilsartan medoxomil and Garlic and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Garlic has been found in some studies to lower blood pressure and may theoretically potentiate the effects of hypotensive agents. A meta-analysis of 11 randomized, placebo-controlled studies showed a mean decrease of 4.6 mmHg for systolic blood pressure and no significant effect for diastolic blood pressure in subjects treated with garlic (most often garlic powder 600 to 900 mg/day, providing 3.6 to 5.4 mg of the active component allicin) compared to placebo. In the subgroup analysis of studies where subjects had a mean baseline blood pressure in the hypertensive range (SBP 140 mmHg or higher; DBP 90 mmHg or higher), mean decrease associated with garlic was 8.4 mmHg and 7.3 mmHg, respectively, for systolic and diastolic blood pressure. There have been no reports of clinical hypotension associated with concomitant use of garlic and antihypertensive agents.
- Richard CL, Jurgens TM "Effects of natural health products on blood pressure." Ann Pharmacother 39 (2005): 712-20
- Tattelman E "Health effects of garlic." Am Fam Physician 72 (2005): 103-6
Generic Name: azilsartan medoxomil
Brand name: Edarbi
Synonyms: Edarbi, Azilsartan
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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