Azithromycin 5 Day Dose Pack and Biktarvy
Determining the interaction of Azithromycin 5 Day Dose Pack and Biktarvy and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Azithromycin may increase the blood levels of bictegravir. This may increase side effects such as diarrhea, nausea, and vomiting. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Coadministration with inhibitors of P-glycoprotein (P-gp) and/or breast cancer resistance protein (BCRP) may increase the plasma concentrations of bictegravir. According to the product labeling, bictegravir is a substrate of both P-gp and BCRP; however, the extent to which each enzymatic pathway contributes to the metabolic clearance of bictegravir has not been reported.
MANAGEMENT: The use of bictegravir with P-gp and/or BCRP inhibitors should generally be avoided. If concomitant use is required, caution and close clinical and laboratory monitoring, including renal function, are recommended. Dosage adjustments may be required whenever a P-gp and/or BCRP inhibitor is added to or withdrawn from therapy.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: azithromycin
Brand name: Azithromycin 3 Day Dose Pack, Azithromycin 5 Day Dose Pack, Zithromax, Zithromax IV, Zithromax Tri-Pak, Zithromax Z-Pak, AzaSite, Zmax
Synonyms: Azithromycin 3 Day Dose Pack
Generic Name: bictegravir / emtricitabine / tenofovir alafenamide
Brand name: Biktarvy
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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