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Azulfidine Tablets and Luminal

Determining the interaction of Azulfidine Tablets and Luminal and the possibility of their joint administration.

Check result:
Azulfidine Tablets <> Luminal
Relevance: 15.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Phenobarbital may slightly increase biliary excretion of sulfasalazine. It has been suggested, however, that no special precautions are necessary when these drugs are coadministered.

References
  • Schroder H, Lewkonia RM, Price Evans DA "Metabolism of salicylazosulfapyridine in healthy subjects and in patients with ulceratice colitis. Effects of colectomy and of phenobarbital." Clin Pharmacol Ther 14 (1973): 802-9
Azulfidine Tablets

Generic Name: sulfasalazine

Brand name: Azulfidine, Azulfidine EN-tabs, Sulfazine

Synonyms: Azulfidine

Luminal

Generic Name: phenobarbital

Brand name: Luminal, Solfoton

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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