Baclofen Intrathecal and Caplacizumab

• Generic Name: baclofen
• Dosage Forms: n.a.
• Other Brand Names: Lioresal Intrathecal, Gablofen, FIRST Baclofen, Lioresal, Ozobax

Intrathecal baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, cerebral palsy, or certain injuries to the spine. Intrathecal baclofen does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Intrathecal baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

Baclofen is delivered by a drug pump directly into the spinal fluid of your back. A doctor will surgically place the pump and monitor the dose of the medication that is delivered by the pump. The dose of intrathecal baclofen will be different for different patients and will depend on the type of muscle tightness that you have.

Intrathecal baclofen is given only by or under the direct supervision of a doctor.

• Generic Name: caplacizumab
• Dosage Forms: n.a.
• Other Brand Names: Cablivi

Caplacizumab is used to treat acquired thrombotic thrombocytopenic purpura (aTTP) in adults. Caplacizumab is given together with immunosuppressant medication and plasma exchange (transfusion).

Caplacizumab may also be used for purposes not listed in this medication guide.