Baclofen Tablets and Carbidopa and Levodopa Enteral Suspension
Determining the interaction of Baclofen Tablets and Carbidopa and Levodopa Enteral Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using levodopa together with baclofen may cause some unpleasant side effects including hallucination, confusion, headache, nausea, vomiting, unsteadiness, and a worsening of parkinsonian symptoms. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of levodopa and oral baclofen has rarely resulted in hallucinations, mental confusion, headache, nausea, and exacerbation of parkinsonian symptoms. The mechanism is unknown.
MANAGEMENT: If concurrent use cannot be avoided, monitoring for mental status changes and worsening of symptoms is advisable.
- Skausig OB, Korsgaard S "Hallucinations and baclofen." Lancet 1 (1977): 1258
- Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: baclofen
Brand name: Lioresal Intrathecal, Gablofen, FIRST Baclofen, Lioresal, Ozobax
Synonyms: Baclofen
Generic Name: carbidopa / levodopa
Brand name: Parcopa, Rytary, Sinemet, Sinemet CR, Duopa
Synonyms: Carbidopa and levodopa, Carbidopa and Levodopa
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Baclofen Tablets-Carbidopa and Levodopa Extended-Release Capsules
- Baclofen Tablets-Carbidopa and Levodopa Extended-Release Tablets
- Baclofen Tablets-Carbidopa and Levodopa ODT
- Baclofen Tablets-Carbidopa and Levodopa Orally Disintegrating Tablets
- Baclofen Tablets-Carbidopa and levodopa Route Not Applicable
- Baclofen Tablets-Carbidopa and Levodopa Tablets
- Carbidopa and Levodopa Enteral Suspension-Bacmin
- Carbidopa and Levodopa Enteral Suspension-Bacteriostatic Sodium Chloride
- Carbidopa and Levodopa Enteral Suspension-Bactimicina Allergy
- Carbidopa and Levodopa Enteral Suspension-Bactine
- Carbidopa and Levodopa Enteral Suspension-Bactine (Lidocaine and Benzalkonium)
- Carbidopa and Levodopa Enteral Suspension-Bactine (Lidocaine Oral Liquid and Solution)