Baycol and Cholestyramine Resin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using cholestyramine together with cerivastatin may decrease the effects of cerivastatin. Cerivastatin should be administered several hours after cholestyramine. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: When administered concomitantly, cholestyramine decreases the bioavailability and peak plasma concentration of cerivastatin, most likely due to adsorption of the statin to the resin. In one study, the bioavailability was reduced by 21% and the peak plasma concentration by 41% under fasting conditions. Separating their administration times by 1 to 5 hours attenuated the effect, resulting in a reduction of 8% to 16% in the bioavailability, depending on length of time between the doses.

MANAGEMENT: If simultaneous therapy with both agents is desired, cerivastatin should be administered several hours after the bile acid binding resin.

Baycol

Generic Name: cerivastatin

Brand name: Baycol

Synonyms: n.a.

What is Baycol?

Cholestyramine Resin

Generic Name: cholestyramine

Brand name: Cholestyramine Light, Prevalite, Questran, Questran Light, Locholest, Locholest Light, Questran Light Packets, Prevalite Packets, Questran Packets

Synonyms: Cholestyramine

What is Cholestyramine Resin?