Bazedoxifene Acetate and Endometrin
Determining the interaction of Bazedoxifene Acetate and Endometrin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using bazedoxifene/conjugated estrogens together with progesterone. Generally, patients treated with bazedoxifene/conjugated estrogens should not receive progesterone or other progestin-containing medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The use of bazedoxifene-conjugated estrogens in combination with progestins has not been evaluated. Safety and efficacy of this combination are unknown.
MANAGEMENT: Women treated with bazedoxifene-conjugated estrogens should not receive progestins, which have often been used to mitigate the risk of endometrial cancer associated with estrogen therapy in patients with an intact uterus. Since the bazedoxifene component is intended to reduce the risk of endometrial hyperplasia, a possible precursor to endometrial cancer, there should be no need for progestin therapy under such circumstances.
- "Product Information. Duavee (bazedoxifene-conjugated estrogens)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
Generic Name: bazedoxifene / conjugated estrogens
Brand name: Duavee
Synonyms: Bazedoxifene and conjugated estrogens, Estrogens (Conjugated/Equine) and Bazedoxifene
Generic Name: progesterone
Brand name: Crinone, Endometrin, FIRST-Progesterone VGS 200, Prochieve, First Progesterone MC10, Menopause Formula Progesterone, Prometrium
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Endometrin-Bazedoxifene and conjugated estrogens
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