Bazedoxifene Acetate and Pralatrexate Intravenous

• Generic Name: bazedoxifene / conjugated estrogens
• Dosage Forms: n.a.
• Other Brand Names: Duavee

Bazedoxifene/conjugated estrogens in fixed combination: Prevention of osteoporosis in postmenopausal women with an intact uterus.

Not FDA-labeled for treatment of osteoporosis in postmenopausal women in the US. Bazedoxifene commercially available in other countries for this use.

Not recommended for prevention of osteoporosis in premenopausal women; safety and efficacy not established.

Bazedoxifene/conjugated estrogens in fixed combination: Management of moderate to severe vasomotor symptoms associated with menopause in women with an intact uterus.

• Generic Name: pralatrexate
• Dosage Forms: n.a.
• Other Brand Names: Folotyn

Pralatrexate injection is used to treat peripheral T-cell lymphoma (PTCL) in patients who have already been treated with other medicines that did not work well. Peripheral T-cell lymphoma is a rare type of cancer that affects certain white blood cells and causes enlarged and swollen lymph nodes in the neck, armpits, and groin.

Pralatrexate belongs to the group of medicines called antineoplastics (cancer medicines). It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other unwanted effects may also occur. Some of these may be serious and must be reported to your doctor.

Pralatrexate is to be administered only by or under the immediate supervision of your doctor.