Beleodaq Injection and DAUNOrubicin and Cytarabine

• Generic Name: belinostat
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Beleodaq

Belinostat is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Belinostat is used to treat peripheral T-cell lymphoma that has relapsed or has not responded to other treatments.

Belinostat was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, non-small cell lung tumors responded to belinostat. However, it has not been shown that belinostat can improve symptoms or lengthen survival time.

Belinostat may also be used for purposes not listed in this medication guide.

• Generic Name: cytarabine liposomal / daunorubicin liposomal
• Dosage Forms: n.a.
• Other Brand Names: Vyxeos

Treatment of newly diagnosed therapy-related AML (t-AML; secondary AML) or AML with myelodysplasia-related changes (AML-MRC) in adults (designated an orphan drug by FDA for this use).

May be used for remission induction as well as consolidation therapy.

Evidence supporting efficacy is based principally on a study performed in patients with high-risk AML (i.e., patients >60 years of age with t-AML or AML-MRC).