Belladonna alkaloids and phenobarbital and Chloroquine
Determining the interaction of Belladonna alkaloids and phenobarbital and Chloroquine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Chloroquine may make PHENobarbital less effective in treating epilepsy or preventing convulsions or seizures. Talk to your doctor if you have ever had epilepsy, convulsions, or seizures, or if you have any questions or concerns. You may need more frequent monitoring by your doctor to safely use both medicines, or your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Chloroquine may lower the convulsive threshold, which may antagonize the action of antiepileptic medications. Seizures have been rarely reported in patients on chloroquine therapy. The mechanism is unknown.
MANAGEMENT: The potential risks and benefits should be evaluated prior to initiating chloroquine in patients on anticonvulsant therapy. In addition, patients with a history of epilepsy should be advised about the risk of chloroquine-induced seizures. Alternative anti-malarial agents may be required. Local treatment guidelines should be consulted.
- "Product Information. Aralen (chloroquine)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: atropine / hyoscyamine / phenobarbital / scopolamine
Brand name: Donnatal, D-Tal, Phenohytro, Chardonna-2, Hyosophen, Donnapine, Elixiral, Bellatal, Spasmolin, Haponal, Antispas, Barbidonna, Donnatal Extentabs, Antispasmodic, Bellalphen, Donnaphen, Spasquid, Alkabel-SR, Bellatal ER, Servira, PB-Hyos, Quadrapax, Phenobarbital with Belladonna Alkaloids
Synonyms: Hyoscyamine, Atropine, Scopolamine, and Phenobarbital
Generic Name: chloroquine
Brand name: Aralen Phosphate, Aralen Hydrochloride
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Belladonna alkaloids and phenobarbital-Chloroquine Oral, Intramuscular
- Belladonna alkaloids and phenobarbital-Chloroquine Phosphate
- Belladonna alkaloids and phenobarbital-Chlorothiazide
- Belladonna alkaloids and phenobarbital-Chlorothiazide Injection
- Belladonna alkaloids and phenobarbital-Chlorothiazide Intravenous
- Belladonna alkaloids and phenobarbital-Chlorothiazide oral/injection
- Chloroquine-Belladonna and Opium
- Chloroquine-Belladonna and opium rectal
- Chloroquine-Belladonna and Opium Suppository
- Chloroquine-Belladonna Tincture
- Chloroquine-Belladonna/Phenobarbital
- Chloroquine-Belrapzo