Belviq and Theraflu Maximum Strength
Determining the interaction of Belviq and Theraflu Maximum Strength and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Lorcaserin may increase the blood levels and effects of chlorpheniramine. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with lorcaserin may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 2D6. The mechanism is decreased clearance due to inhibition of CYP450 2D6 activity by lorcaserin. In a study consisting of 21 CYP450 2D6 extensive metabolizers, administration of the probe substrate dextromethorphan in combination with lorcaserin 10 mg twice daily for 4 days increased dextromethorphan peak concentrations (Cmax) by approximately 76% and systemic exposure (AUC) by approximately 2-fold.
MANAGEMENT: Caution is advised if lorcaserin is prescribed concomitantly with medications that undergo metabolism by CYP450 2D6, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever lorcaserin is added to or withdrawn from therapy.
- "Product Information. Belviq (lorcaserin)." Eisai Inc, Teaneck, NJ.
Generic Name: acetaminophen / chlorpheniramine / pseudoephedrine
Brand name: Alka-Seltzer Plus Cold Liquigel, Comtrex Allergy Sinus, Comtrex Allergy Sinus Maximum Strength, Kolephrin, Sinutab Ex-Strength, Theraflu Maximum Strength, Singlet, Simplet, Tricom, Theraflu Flu and Cold Medicine Powder, Codimal, Tylenol Gelcap Allergy Sinus, Theraflu Sore Throat Maximum Strength, Allerest Sinus, Tylenol Cold-Child, Tylenol Allergy Sinus Caplet, Tylenol Allergy Sinus Geltab, Comtrex Allergy Sinus Night and Day, Allerest Headache Strength, Sinarest Extra Strength, Sinarest, Children's Tylenol Cold Multi-Symptom, Tylenol Allergy Sinus Gelcap, Children's Tylenol Cold, Triaminicin, Sinutab Maximum Strength Caplets, Sinutab Maximum Strength Non-Drowsy, Actifed Cold & Sinus, Theraflu Cold & Sore Throat, Theraflu Flu & Sore Throat, Allergy Sinus Maximum Strength, Cold Medicine Plus, EQ Cold Plus, Complete Sinus Relief, Sinadrin PE Complete Sinus Relief
Synonyms: Acetaminophen, chlorpheniramine, and pseudoephedrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Belviq-Theraflu Nighttime Severe Cold
- Belviq-Theraflu Nighttime Severe Cough and Cold
- Belviq-Theraflu PowerPods (Acetaminophen, Dextromethorphan, and Phenylephrine Pods)
- Belviq-Theraflu PowerPods (Acetaminophen, Diphenhydramine, and Phenylephrine Pods)
- Belviq-Theraflu Severe Cold & Congestion
- Belviq-Theraflu Severe Cold & Congestion Non-Drowsy
- Theraflu Maximum Strength-Belviq XR
- Theraflu Maximum Strength-Benadryl
- Theraflu Maximum Strength-Benadryl Allergy (Diphenhydramine Chewable Tablets and Orally-Disintegrating Tablets)
- Theraflu Maximum Strength-Benadryl Allergy (Diphenhydramine Elixir, Liquid, and Syrup)
- Theraflu Maximum Strength-Benadryl Allergy Sinus Headache
- Theraflu Maximum Strength-Benadryl Allergy Ultratabs