Belviq XR and EQ Children’s Cold
Determining the interaction of Belviq XR and EQ Children’s Cold and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Lorcaserin may increase the blood levels and effects of chlorpheniramine. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with lorcaserin may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 2D6. The mechanism is decreased clearance due to inhibition of CYP450 2D6 activity by lorcaserin. In a study consisting of 21 CYP450 2D6 extensive metabolizers, administration of the probe substrate dextromethorphan in combination with lorcaserin 10 mg twice daily for 4 days increased dextromethorphan peak concentrations (Cmax) by approximately 76% and systemic exposure (AUC) by approximately 2-fold.
MANAGEMENT: Caution is advised if lorcaserin is prescribed concomitantly with medications that undergo metabolism by CYP450 2D6, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever lorcaserin is added to or withdrawn from therapy.
- "Product Information. Belviq (lorcaserin)." Eisai Inc, Teaneck, NJ.
Generic Name: acetaminophen / chlorpheniramine / pseudoephedrine
Brand name: Alka-Seltzer Plus Cold Liquigel, Comtrex Allergy Sinus, Comtrex Allergy Sinus Maximum Strength, Kolephrin, Sinutab Ex-Strength, Theraflu Maximum Strength, Singlet, Simplet, Tricom, Theraflu Flu and Cold Medicine Powder, Codimal, Tylenol Gelcap Allergy Sinus, Theraflu Sore Throat Maximum Strength, Allerest Sinus, Tylenol Cold-Child, Tylenol Allergy Sinus Caplet, Tylenol Allergy Sinus Geltab, Comtrex Allergy Sinus Night and Day, Allerest Headache Strength, Sinarest Extra Strength, Sinarest, Children's Tylenol Cold Multi-Symptom, Tylenol Allergy Sinus Gelcap, Children's Tylenol Cold, Triaminicin, Sinutab Maximum Strength Caplets, Sinutab Maximum Strength Non-Drowsy, Actifed Cold & Sinus, Theraflu Cold & Sore Throat, Theraflu Flu & Sore Throat, Allergy Sinus Maximum Strength, Cold Medicine Plus, EQ Cold Plus, Complete Sinus Relief, Sinadrin PE Complete Sinus Relief
Synonyms: Acetaminophen, chlorpheniramine, and pseudoephedrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Belviq XR-EQ Cold Plus
- Belviq XR-EQ Cold Relief Complete
- Belviq XR-EQ Cold/Cough Plus
- Belviq XR-EQ Daytime Cold/Flu Relief
- Belviq XR-EQ Flu Relief
- Belviq XR-EQ Flu/Severe Cold/Congestion
- EQ Children’s Cold-Benadryl
- EQ Children’s Cold-Benadryl Allergy (Diphenhydramine Chewable Tablets and Orally-Disintegrating Tablets)
- EQ Children’s Cold-Benadryl Allergy (Diphenhydramine Elixir, Liquid, and Syrup)
- EQ Children’s Cold-Benadryl Allergy Sinus Headache
- EQ Children’s Cold-Benadryl Allergy Ultratabs
- EQ Children’s Cold-Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets)
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold 
Belviq XR - EQ Children’s Cold