Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets) and Digoxin oral/injection
Determining the interaction of Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets) and Digoxin oral/injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using digoxin together with phenylephrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using phenylephrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.
MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.
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- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
- "Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: acetaminophen / diphenhydramine / phenylephrine
Brand name: Benadryl Allergy/Cold, Tylenol Allergy Multi-Symptom, Benadryl Allergy & Sinus Headache, Delsym Cough Plus Cold Night Time, Mucinex Fast-Max Night Time Cold and Flu, Robitussin Nighttime Multi-Symptom Cold, Sudafed PE Severe Cold, Theraflu Severe Cold & Cough Nighttime, Theraflu Warming Flu & Sore Throat, Theraflu Warming Sinus & Cold, Theraflu Warming Severe Cold Nighttime, Benadryl Allergy & Cold, Sudafed PE Nighttime Cold, Tylenol Allergy Multi-Symptom Nighttime, Theraflu Nighttime Severe Cough & Cold, Children's Delsym Cough Plus Cold Night Time, Children's Mucinex Night Multi-Symp Cold, Children's Dimetapp Multi-Symptom Cold & Flu, Theraflu ExpressMax Nighttime Severe C&C, Theraflu PowerPods Nighttime Severe Cold, Theraflu Warming Relief Nighttime Severe Cold
Synonyms: n.a.
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digoxin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets)-Digoxin Tablets
- Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets)-Dihydro CP Syrup
- Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets)-Dihydrocodeine BPM Phenyleph HCl
- Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets)-Dihydrocodeine, Aspirin, and Caffeine
- Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets)-Dihydroergotamine
- Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Phenylephrine Tablets)-Dihydroergotamine injection
- Digoxin oral/injection-Benadryl Allergy/Cold (Acetaminophen, Diphenhydramine, and Pseudoephedrine Tablets)
- Digoxin oral/injection-Benadryl Injection
- Digoxin oral/injection-Benadryl Itch Stopping
- Digoxin oral/injection-Benadryl-D
- Digoxin oral/injection-Benazepril
- Digoxin oral/injection-Benazepril and Hydrochlorothiazide