Bendamustine Hydrochloride and Roxicodone (Oxycodone Concentrate)

• Generic Name: bendamustine
• Dosage Forms: n.a.
• Other Brand Names: Belrapzo, Bendeka, Treanda

Treatment of chronic lymphocytic leukemia (CLL) (designated an orphan drug by FDA for this use).

Prolonged progression-free survival and increased overall response rate observed with bendamustine compared with chlorambucil in patients with previously untreated, Binet stage B or C (Rai stages I–IV) CLL. Incidence of adverse effects generally also higher with bendamustine than with chlorambucil.

Efficacy of bendamustine relative to first-line therapies other than chlorambucil not established.

Treatment of rituximab-refractory, indolent, B-cell non-Hodgkin’s lymphoma (NHL).

Use in combination with rituximab for treatment of previously untreated advanced-stage indolent NHL or for treatment of previously untreated advanced-stage mantle cell lymphoma is a reasonable choice (accepted, with possible conditions); however, consider histologic subtype of NHL when selecting a combination chemotherapy regimen.

Use in combination with rituximab for treatment of relapsed or refractory indolent NHL or for treatment of relapsed or refractory mantle cell lymphoma is recommended (accepted).

• Generic Name: oxycodone
• Dosage Forms: tablet
• Other Brand Names: Oxaydo, Oxycontin, Oxyfast, Roxicodone, Xtampza ER, Oxecta, Oxycontin, Roxybond, Xtampza ER; oxycodone is also present in the following combination drugs: Combunox, Endocet, Endodan, Moxduo, Oxycodan, Percocet, Percodan, Primlev, Roxicet, Xartemis XR, and others, OxyIR, Roxybond

• It is used to ease pain.