Bendamustine Intravenous and Primaquine Phosphate
Determining the interaction of Bendamustine Intravenous and Primaquine Phosphate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Primaquine may increase the blood levels of bendamustine in some patients. This can increase the risk of side effects that affect your bone marrow function, resulting in low numbers of different types of blood cells. You may be more likely to develop anemia, bleeding problems, or infections. Contact your doctor if you experience potential signs and symptoms of these conditions such as paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inhibitors of CYP450 1A2 may increase the plasma concentrations of bendamustine, which has been shown in vitro to be metabolized by the isoenzyme.
MANAGEMENT: Caution is advised if bendamustine is used in combination with CYP450 1A2 inhibitors. Close monitoring for toxicity (e.g., neutropenia, thrombocytopenia, anemia, leukopenia, infections, bleeding complications) is recommended, and the bendamustine dosage adjusted as necessary.
- "Product Information. Treanda (bendamustine)." Cephalon Inc, West Chester, PA.
Generic Name: bendamustine
Brand name: Belrapzo, Bendeka, Treanda
Synonyms: Bendamustine
Generic Name: primaquine
Brand name:
Synonyms: Primaquine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bendamustine Intravenous-Primatene
- Bendamustine Intravenous-Primatene Asthma
- Bendamustine Intravenous-Primatene Mist
- Bendamustine Intravenous-Primaxin IM
- Bendamustine Intravenous-Primaxin IV
- Bendamustine Intravenous-Prime Health Kids
- Primaquine Phosphate-Bendeka
- Primaquine Phosphate-Bendroflumethiazide and nadolol
- Primaquine Phosphate-BeneFIX
- Primaquine Phosphate-Benefix Intravenous
- Primaquine Phosphate-Benemid
- Primaquine Phosphate-BENGAY Ultra