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Benemid and Heparin and Sodium Chloride

Determining the interaction of Benemid and Heparin and Sodium Chloride and the possibility of their joint administration.

Check result:
Benemid <> Heparin and Sodium Chloride
Relevance: 19.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

A single case report suggests that probenecid may enhance the anticoagulant effects of heparin; however, causality was not definitely determined. The risk of bleeding may be increased. During concomitant therapy, the patient should be monitored for excessive anticoagulation.

References
  • Sanchez G "Enhancement of heparin effect by probenicid." N Engl J Med 292 (1975): 48
Benemid

Generic Name: probenecid

Brand name: Benemid

Synonyms: n.a.

Heparin and Sodium Chloride

Generic Name: heparin

Brand name: Hep-Pak, Heparin Lock flush, Hep-Pak CVC, Hep-Lock, Heparin Sodium ADD-Vantage, HepFlush

Synonyms: Heparin Injection, Heparin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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